Pharmaceutical Intermediates

PharmIntermediats

OVERVIEW

Varsal has extensive technical capabilities in developing and manufacturing sophisticated Pharmaceutical Intermediates at Varsal’s GMP-compliant facilities or at Varsal and customer-approved partners. We also custom manufacture other Pharmaceutical upon request, please contact us for more information!

Toluenesulfonylmethyl Isocyanide (TosMIC)

  • Other names: p-Toluenesulfonylmethylisocyanide, TosMIC
  • Molecular weight: 195.24
  • Appearance: colorless crystalline powder, off-white to yellowish
  • CAS#: 36635-61-7

 

Used as an intermediate for various reasons, including in the Van Leusen reaction which is used to convert aldehydes to nitriles or in the preparation of oxazoles and imidazoles.

  • Pharmaceutical
  • Agriculture
  • Food
  • Electronics

Varsal is one of the world’s leading producers of TosMIC, and one of the few producers capable of producing large-scale, pharma-grade material. Varsal’s proprietary manufacturing and treatment process allows it to produce extremely high purity material with low residual impurities, low loss on drying, and low residue on ignition, leading to maximal yield and product quality for Varsal’s customers.

N,N’-dicyclohexylcarbodiimide (DCC)

  • Other names: DCC
  • Molecular weight: 206.33
  • Appearance: white to slight yellow crystalline solid
  • CAS#: 538-75-0

Used as an intermediate for various reasons, including to couple amino acids during artificial peptide synthesis.

  • Pharmaceutical

Varsal’s material has extremely high purity with low residual impurities and low loss on drying, leading to maximal yield and product quality for Varsal’s customers.

Acetamidine Hydrochloride

  • Other names: ethanimidamide, ethanamidine acetimidamide, carboxamidine, carboximidamide
  • Molecular weight: 94.54
  • Appearance: white or yellowish long prismatic crystals
  • CAS#: 124-42-5

Used as a Vitamin B1 building block, strong non-ionic nucleophile, intermediate in antihypertensive APIs, guanidine derivative.

  • Pharmaceutical
  • Personal Care
  • Industrial

Varsal leverages its deep chlorination and technical manufacturing resources to produce material that has extremely high purity with low residual impurities, low moisture and low loss on drying, leading to maximal yield and product quality for Varsal’s customers.

3-oxo-2-phenylbutanamide

  • Other names: 2-phenyl-acetoacetic acid amide, 2-Phenyl-acetessigsaeure-amid
  • Molecular weight: 177.20
  • Appearance: white powder
  • CAS#: 4433-77-6

Used as a pharmaceutical intermediate.

  • Pharmaceutical

Varsal leverages its deep technical manufacturing resources to produce material that has extremely high purity with low residual impurities, low moisture and low loss on drying, leading to maximal yield and product quality for Varsal’s customers.

Mechlorethamine Hydrochloride

  • Other names: chloramine
  • Molecular weight: 192.52
  • Appearance: white crystalline powder
  • CAS#: 55-86-7

API in anti-tumor drugs (DNA alkylation of guanines), psoriasis, vitiligo, mycosis fungoides, can also be used as an immunosuppressant.

  • Pharmaceutical

Varsal leverages its deep chlorination and technical manufacturing resources to produce material that has extremely high purity with low residual impurities, low moisture, low residue on ignition and low loss on drying, leading to maximal yield and product quality for Varsal’s customers.

Trifluorotoluene

  • Other names: Benzotrifluoride (BTF), α,α,α-Trifluorotoluene
  • Molecular weight: 146.11
  • Appearance: clear, colorless liquid
  • CAS#:98-08-8

Used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.

  • Pharmaceutical
  • Agriculture

Varsal’s material has extremely high purity with low residual impurities, leading to maximal yield and product quality for Varsal’s customers.

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